ヒト血清中の内因性ステロイド物質(13種)の同時定量分析

ヒト血清中の内因性ステロイド物質(13種)の同時定量分析

 CompoundIon ModeRT
( min )		MRMLOQ
( ng/mL )

Range
( ng/mL )

Blank Serum
( ng/mL )
1 DHEAS ESI - 1.05 367.2 > 97.0 0.0025 0.0025 - 25 1360
2 Estriol ESI - 2.00 237.2 > 17.10, 145.0 0.05 0.05 - 250 n.d.
3 Aldosterone ESI + 2.32 361.3 > 343.3, 315.2 0.005 0.005 - 50 n.d.
4 Cortisol ESI + 3.21 363.2 > 327.2, 121.1 0.0025 0.0025 - 25 149
5 Corticosterone ESI + 4.41 347.3 > 329.3, 311.2 0.01 0.01 - 25 2.94
6 11-Deoxycortisol ESI + 4.78 347.3 > 109.1, 97.0 0.0025 0.0025 - 25 0.22
7 Androsteronedione ESI + 5.65 287.2 > 109.1, 97.0 0.0025 0.0025 - 25 0.77
IS Estradiol-d5 ESI - 5.70 276.2 > 147.1      
8 Estradiol ESI - 5.72 271.2 > 183.1, 145.1 0.05 0.05 - 500  
9 Estrone ESI - 5.82 269.2 > 183.1, 145.1 0.05 0.05 - 500 u'q'
IS Testosterone-d3 ESI + 6.24 292.2 > 97.0     u'q'
10 Testosterone ESI + 6.27 289.2 > 97.0 0.0025 0.0025 - 25  
11 17α - Hydroxyprogetserone ESI + 6.68 331.3 > 109.1, 97.0 0.0025 0.0025 - 25 3.94
IS DHEA-d5 ESI + 6.93 276.2 > 258.2     0.24
12 DHEA ESI + 6.96 271.2 > 253.2, 197.2 0.025 0.0025 - 250 n.d.
IS Progesterone-d9 ESI + 8.30 324.3 > 100.2      
13 Progesterone ESI + 8.30 315.3 > 109.2, 97.0 0.0025 0.0025 - 25 0.05
  • 5fg ( on column ) から定量可能 ( cortisol )
  • Positive ・Negative 同時測定
  • 簡便・迅速・高感度な内因性ステロイド類の定量が可能


Counts vs. Acquisition Time (min)

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